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KMID : 0360220090500040603
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Journal of the Korean Ophthalmological Society
2009 Volume.50 No. 4 p.603 ~ p.611
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The Effects of Sutureless Faden Operation With Several Materials in Rabbit Models
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Seo Jeong-Hun
Lee Seong-Jun
Lee Ok-Jun
Choi Mi-Young
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Abstract
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Purpose: To investigate the effects of sutureless faden operation to eliminate suture-related perioperative risks in a rabbit model.
Methods: Twenty-eighty superior recti muscles of 14 rabbits were subjected to faden operation, at a distance of 6 mm from the insertion of the muscle. They were divided into four groups of 7 muscles each: group A, Beriplast-P ; group B, Bardⓡ mesh (12×2 mm); group C, Surgiproⓡ mesh (6×2 mm); group D, Surgiproⓡ mesh (6×6 mm). Rabbits were sacrificed and the eyes were enucleated. The operative field was examined upon dissection, 4 weeks after the surgery. Histopathologic sections were examined for the degree (grade 0 to 4) of inflammation, fibrosis, atrophy and/or degeneration of muscle fiber.
Results: Grossly, there was a mild adhesion at the myopexy site in group A, while there was greater adhesion at the myopexy site in groups B, C and D. Group B produced a pronounced adhesion, and the mesh firmly adhered to the sclera as well as to adjacent tissue. Upon histologic examination, group A showed a mild inflammatory reaction and fibrosis, whereas groups B and D showed a moderate inflammatory reaction and fibrosis. The degree of fibrosis in group D was more severe than that in group A (p<0.008), and there was no statistical significance among the other groups (p>0.05). There was atrophy and degeneration in the muscle fiber in all groups, with the exception of group D.
Conclusions: In the rabbit model, 6×6 mm sized Surgiproⓡ mesh may be the best material in sutureless faden operation.
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KEYWORD
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Bardⓡ mesh, Beriplast-P ⓡ, Fadenoperation, Surgiproⓡ mesh, Sutureless strabismus surgery
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